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Scottish Palliative Care Guidelines print pdf

Drug Administration Table: Unlicensed Routes

Drug Administration Table – Unlicensed Routes
Many of the drugs below are commonly given by subcutaneous bolus or infusion in palliative care patients regardless of their licensed routes of administration
Note: If administering cyclizine or haloperidol ensure line is flushed before and after use with water for injection.


Drug

CSCI

SC Inj

IM inj

IV inj

Sublingual

Buccal

Topical

Oral

Intranasal

Via stoma

Nebulised

Adrenaline 1 in 1000

N/A

N/A

YES

N/A

N/A

N/A

N/A

N/A

N/A

Alfentanil

YES

N/A

N/A

N/A

N/A

Carbocisteine

N/A

N/A

N/A

N/A

N/A

N/A

N/A

YES

N/A

N/A

Clonazepam

YES

YES

YES

N/A

N/A

YES

N/A

N/A

N/A

Cyclizine

YES

YES

N/A

N/A

YES

N/A

N/A

N/A

Dexamethasone Injection Hameln brand

YES

YES

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Dexamethasone Injection Hospira brand

YES

YES

YES

YES

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Diamorphine Injection

YES

YES

YES

YES

N/A

N/A

N/A

N/A

Diazepam Rectal

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Diclofenac

Not
reccomended

YES

Infusion

N/A

N/A

YES

YES

N/A

N/A

Glycopyrronium

YES

YES

N/A

N/A

N/A

N/A

N/A

Haloperidol Injection

YES

YES

N/A

N/A

YES

N/A

N/A

N/A

Hydromorphone

N/A

N/A

N/A

YES

N/A

N/A

N/A

Hyoscine Butylbromide

YES

YES

N/A

N/A

N/A

YES
(poor absorption)

N/A

N/A

N/A

Hyoscine Hydrobromide

YES

YES

N/A

YES

YES

N/A

N/A

N/A

N/A

Ketamine

YES

YES

N/A

N/A

N/A

Ketorolac

YES

YES

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Levomepromazine

YES

YES

YES

N/A

N/A

N/A

N/A

N/A

Lorazepam

†(caution)

YES

YES

N/A

N/A

YES

N/A

N/A

N/A

Metoclopramide Injection

YES

YES

N/A

N/A

N/A

YES

N/A

N/A

N/A

Midazolam Injection- Roche brand

YES

YES

N/A

N/A

N/A

N/A

Midazolam Injection - Phoenix brand

YES

N/A

N/A

N/A

N/A

Midazolam Buccal Solution

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Morphine sulfate

YES

YES

YES

N/A

N/A

YES

YES

N/A

N/A

N/A

Octreotide Injection

YES

N/A

YES

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Oxycodone Injection

YES

YES

YES

N/A

N/A

N/A

YES

N/A

N/A

N/A

Phenobarbital

†(not recommended)

YES

YES

N/A

N/A

N/A

YES

N/A

N/A

N/A

Sodium Chloride 0.9%

YES

N/A

N/A

N/A

YES

N/A

YES

Sucralfate

N/A

N/A

N/A

N/A

N/A

N/A

YES

N/A

N/A

N/A

Tranexamic Acid

N/A

N/A

N/A

YES

N/A

N/A

YES

N//A

N/A

N/A

Key:
YES - indicates a licensed route,
NA indicates this route is Not Applicable,
indicates that this route is unlicensed

Adapted from information prepared initially Elayne Harris, Joe Harrison, Susan Addie NHS Greater Glasgow & Clyde 2006

Draft v3  5th Sep 2014  A MacRobbie